Our People
Biography
Dr.. Kim Hei-Man Chow is an Assistant Professor in the School of Life Sciences at the Chinese University of Hong Kong. She received her graduate training at the University of Hong Kong, pursued postdoctoral research at Cornell University, and later held a research assistant professorship at the Hong Kong University of Science and Technology under the supervision of Prof. Karl Herrup. Dr. Chow has been honored with several prestigious international fellowships, including the U.S. National Academy of Medicine International Health Policy Fellowship, the Alzheimer’s Association Research Fellowship, and the World Economic Forum Global Future Council Fellowship. Her research focus is on investigating how the peripheral body’s metabolic status influence brain homeostasis, aging and vulnerability to Alzheimer’s disease and related dementias.
Kim CHOW
Assistant Professor, School of Life Sciences
Research Interests
- Brain metabolic changes in Alzheimer’s disease and related dementia
- Neuronal senescence in brain aging and diseases
- Endocrine and brain health crosstalk
Awards
- Awardee, Faculty Young Researcher Award, Faculty of Science, The Chinese University of Hong Kong, Hong Kong, 02/2025.
- Awardee, International Health Policy Fellowship, The National Academy of Medicine (NAM), USA, 07/2023-12/2025.
- Awardee, Faculty Exemplary Teaching Award, Faculty of Science, The Chinese University of Hong Kong, Hong Kong. 04/2022.
- Awardee, Excellent Young Scientists Fund (Hong Kong and Macau), National Natural Science Foundation of China, China. 09/2021.
- Awardee, Young Investigator Award, CUHK East Meets West Symposium 2019, Hong Kong. 09/2019.
Selected publications
- Deng Wu, Jacquelyne Ka Li Sun, Kim Hei-Man Chow. (2024) Neuronal cell cycle re-entry events in the aging brain are more prevalent in neurodegeneration and lead to cellular senescence. PLOS Biology. 2024 Apr 23;22(4):e3002559. doi: 10.1371/journal.pbio.3002559 [Corresponding author, Clarivate Ranking: 5/109 Biology (Q1), Clarivate impact factor 2023: 7.8]
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- PLOS Biology editors’ top picks for 2024:https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002985
- PLOS Biology Selected press release and highlight:https://www.eurekalert.org/news-releases/1041360
- CUHK press release: https://www.cpr.cuhk.edu.hk/en/press/cuhk-team-develops-a-big-data-analysis-method-to-study-senescent-neurons-providing-new-directions-for-precision-medicine-in-neurodegenerative-diseases/
- Hong Kong Laurate Forum Newsletter, Invited Feature Story: https://hklaureateforum.org/en/newsletter-jun-2024-issue-25
- Deng Wu, Xiaoman Bi, Kim Hei-Man Chow.(2024) Identification of female-enriched and disease-associated microglia (FDAMic) contributes to sexual dimorphism in late-onset Alzheimer’s disease. Journal of Neuroinflammation. 2024 Jan 4;21(1):1. doi: 10.1186/s12974-023-02987-4. [Corresponding author, Clarivate Ranking: 13/181 in Immunology (Q1), Clarivate impact factor2023: 9.3]
- Deng Wu, Xiaoman Bi, Peihu Li, Dahua Xu, Jianmin Qiu, Kongning Li, Shaojiang Zheng, Kim Hei-Man Chow.(2023) Enhanced insulin-regulated phagocytic activities support extreme health span and longevity in multiple populations. Aging Cell 2023 Mar 8;e13810. [Lead co-corresponding author, Clarivate Ranking: 5/74 in Geriatrics & Gerontology (Q1), Clarivate impact factor 2023: 8.0]
- Jacquelyne Ka-Li Sun, Deng Wu, Genper Chi-Ngai Wong, Tsun-Ming Lau, Meigui Yang, Ronald P Hart, Kin-Ming Kwan, Ho-Yin Edwin Chan, Hei-Man Chow. (2023) Chronic alcohol metabolism results in DNA repair infidelity and cell-cycle-induced senescence in neurons. Aging Cell2023 Feb; 22(2):e13772. [Corresponding author, Clarivate Ranking: 5/74 in Geriatrics & Gerontology (Q1), Clarivate impact factor 2023: 8.0]
- Hei-Man Chow,Meng Shi, Aifang Cheng, Yuehong Gao, Guimiao Chen, Xuan Song, Raphaella Wai Lam So, Jie Zhang, Karl Herrup. (2019) Age-related hyperinsulinemia leads to insulin resistance in neurons and cell-cycle-induced senescence. Nature Neuroscience. 2019 Nov;22(11):1806-1819. doi: 10.1038/s41593-019-0505-1. [Co-corresponding author, Clarivate Ranking: 4/310 in Neurosciences (Q1), Clarivate impact factor 2023: 21.2]
- F1000 Prime (2-Star article): https://connect.h1.co/article/736782348?bd=1
