Biography
Dr. Sai Kam Hui received his Bachelor’s degree in medical engineering (2005) and Doctor of Philosophy’s degree in electrical and electronic engineering (2009) from The University of Hong Kong.
Dr. Hui received his postdoctoral training in MRI from three different institutes in the United States, namely the Methodist Hospital at Houston (2009), The University of Texas Health Science Center at San Antonio (2010), and the Medical University of South Carolina (2011). He was appointed as Research Assistant Professor at The Center for Biomedical Imaging, Medical University of South Carolina in 2012. He left the United States in 2013.
Dr. Hui returned to Hong Kong and joined the Department of Diagnostic Radiology, The University of Hong Kong, as Research Assistant Professor between 2013 and 2020. He was appointed as Assistant Professor of Rehabilitation Sciences at The Hong Kong Polytechnic University between 2020 and 2022.
Dr. Hui joined the Chinese University of Hong Kong in 2022 and has since held a joint appointment between the Department of Imaging and Interventional Radiology, and Department of Psychiatry with funding support from Lui Che Woo Institute of Innovative Medicine as Assistant Professor. He is also the Director of the Research Center for Medical Imaging Computing.
Edward HUI
Assistant Professor, Department of Imaging and Interventional Radiology &
Department of Psychiatry
Research Interests
Dr. Hui’s overall goals are to develop neuroimaging biomarkers for disease diagnosis and prognosis, and to fill the critical knowledge in the neuroarchitectural underpinnings of stroke recovery using advanced magnetic resonance imaging and medical image analysis methods. He is also keenly interested in developing artificial intelligence (AI) models to aid clinical decision making. Dr. Hui is currently developing AI models, including foundation models and large language models, for automatic generation of annotated radiology reports for chest X-ray applications.
Awards
Finalist to the Mario Stefanelli Award for the Best Student Paper
Selected publications
- DoKE: Domain knowledge-enhanced multimodal large language model-based framework for chest X-ray follow-up medical visual question answering.
Wang Z, Deng Q, So TY, Chiu WH, Hui ES*
Biomedical Signal Processing and Control. 2026 Jul 1;120:109908 - Grounded knowledgeenhanced medical vision-language pre-training for chest X-ray.
Deng Q, Huang Z, Wang Y, Wang Z, Wang Z, Zhang X, Dou Q, Hui YY, Hui ES*
Biomedical Signal Processing and Control. 2026 Feb 1;112:108416 - Disease probability-enhanced follow-up chest X-ray radiology report summary generation.
Wang Z, Deng Q, So TY, Chiu WH, Lee K, Hui ES*
Scientific Reports. 2025 Jul 24;15(1):26930 - Illuminating the Unseen: Advancing MRI Domain Generalization Through Causality.
Wang Y, Zeng T, Liu F, Dou Q, Cao P, Chang HC, Deng Q, Hui ES*
Medical Image Analysis. 2025 Jan 16:103459 - The structural-functional-connectivity coupling of the aging brain.
Zhang H, Cao P, Mak HKF, Hui ES*
GeroScience. 2024 Aug;46(4):3875-3887 - Time-resolved magnetic resonance fingerprinting for radiotherapy motion management.
Li T, Cui D, Hui ES*, Cai J.
Medical Physics. 2020 Dec;47(12):6286-6293 - The effect of the total small vessel disease burden on the structural brain network.
Xu X, Lau KK, Wong YK, Mak HKF, Hui ES*
Scientific Reports. 2018 May 10;8(1):7442 - Diffusional kurtosis and diffusion tensor imaging reveal different time-sensitive stroke-induced microstructural changes.
Weber RA, Hui ES, Jensen JH, Nie X, Falangola MF, Helpern JA, Adkins DL.
Stroke. 2015 Feb;46(2):545-50 - Stroke assessment with diffusional kurtosis imaging.
Hui ES, Fieremans E, Jensen JH, Tabesh A, Feng W, Bonilha L, Spampinato MV, Adams R, Helpern JA.
Stroke. 2012 Nov;43(11):2968-73 - LINGO-1 antagonist promotes spinal cord remyelination and axonal integrity in MOG-induced experimental autoimmune encephalomyelitis.
Mi S, Hu B, Hahm K, Luo Y, Hui ES, Yuan Q, Wong WM, Wang L, Su H, Chu TH, Guo J, Zhang W, So KF, Pepinsky B, Shao Z, Graff C, Garber E, Jung V, Wu EX, Wu W.
Nature Medicine. 2007 Oct;13(10):1228-33
